Is the movie 50 First Dates realistic? Amnesia in movies is often problematic. There are two types of amnesia: anterograde and retrograde. In retrograde amnesia, people lose some memories from their past, but are still able to form new memories. Anterograde amnesia is the opposite: past memories are intact but patients are unable to lay down new memories. This is the kind of amnesia depicted in 50 First Dates. However, anterograde amnesia doesn’t “reset” every night like in this film. Rather, events are forgotten as soon as they leave working memory, or as soon as the brain stops actively working on the information. In practice, this means forgetting will occur every few minutes. The movie would have been very different if it portrayed true anterograde amnesia!